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[外来雌激素——对后代构成威胁?]

[Xenoestrogens--danger for the future generations?].

作者信息

Sirakov M

出版信息

Akush Ginekol (Sofiia). 2004;43(4):39-45.

PMID:15318543
Abstract

In this work I would like to speak about a group of substances which invisible are present in our environment. We come across with them every day. We eat them, drink them, breathe them and use them at work, at home and in the garden. They are present in soil, water, air and food, household products, packing materials, probably in the breast milk and during development in our mother's womb. These substances are "xenoestrogens". "Xeno" literally means foreign. So xenoestrogens means foreign estrogens. They are also known as: endocrine or hormone disrupters, environmental estrogens, hormonally active agents (EPA), estrogenic substances, estrogenic xenobiotics, and bioactive chemicals. The human health risks, that may be associated with these low-level but constant exposures are still largely unknown and highly controversial. May be, more knowledge in this area could give us an answer to the questions which every one of us asks many times: what is the reason of appearance of this or that disease or condition, why suddenly, without visible reason childs' breasts start to grow, the menstrual cycle break off, why prescribed by me therapy does not work? Etc....

摘要

在这项工作中,我想谈谈一类存在于我们环境中却不可见的物质。我们每天都会接触到它们。我们食用它们、饮用它们、呼吸它们,并且在工作、居家及花园中使用它们。它们存在于土壤、水、空气、食物、家居用品、包装材料中,可能还存在于母乳以及我们在母亲子宫内发育期间。这些物质就是“外源性雌激素”。“xeno”字面意思是外来的。所以外源性雌激素就是外来雌激素。它们也被称为:内分泌或激素干扰物、环境雌激素、激素活性物质(美国环境保护局定义)、雌激素物质、雌激素性外源性生物活性物质以及生物活性化学物质。与这些低剂量但持续接触相关的人类健康风险在很大程度上仍不为人知且极具争议性。或许,该领域更多的知识能为我们每个人多次提出的问题提供答案:某某疾病或状况出现的原因是什么,为什么孩子的乳房会突然毫无明显原因地开始发育,月经周期为何中断,为什么我开的治疗方法不起作用?等等……

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