Babilé R, Queinnec G, Berland H M, Darré R
C R Seances Soc Biol Fil. 1978;172(3):546-53.
Different concentrations of food additives were introduced in cultures of pig lymphocytes. No special chromosomal damage were induced by anticoccidians. On the contrary some antibiotics caused chromosomic anomalies. Chloramphenicol and furazolidone assayed in vitro and in vivo had also an antimitotic effect. The purpose of this work was to know the cytotoxic effect of some substances: a preliminary and cheap test could be a cytogenetic examination in vitro.
将不同浓度的食品添加剂引入猪淋巴细胞培养物中。抗球虫药未诱导出特殊的染色体损伤。相反,一些抗生素导致了染色体异常。体外和体内检测的氯霉素和呋喃唑酮也有抗有丝分裂作用。这项工作的目的是了解某些物质的细胞毒性作用:一种初步且廉价的检测方法可能是体外细胞遗传学检查。