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在资源有限的环境中扩大艾滋病毒治疗项目:海地农村的经验。

Scaling-up HIV treatment programmes in resource-limited settings: the rural Haiti experience.

作者信息

Koenig Serena P, Léandre Fernet, Farmer Paul E

机构信息

Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

AIDS. 2004 Jun;18 Suppl 3:S21-5. doi: 10.1097/00002030-200406003-00005.

Abstract

OBJECTIVE

To scale-up a successful HIV/AIDS treatment project and provide comprehensive care to an entire Département du Centre (population 550 000) in rural Haiti, thereby demonstrating that community-based treatment of HIV is feasible and highly effective in resource-limited settings, and serving as a successful model for others to replicate.

PARTICIPANTS

In the Département du Centre of rural Haiti comprehensive HIV and tuberculosis treatment is provided free of charge to anyone who presents for care. All those who meet clinical enrolment criteria are treated with highly active antiretroviral therapy (HAART).

INTERVENTION

HAART was provided in the context of a comprehensive programme of HIV, tuberculosis (TB), sexually transmitted disease (STD) of the project, treatment and prevention, and women's health services at four sites in the first year. At each site, the medical facility was renovated, additional staff were hired as needed, and a network of accompagnateurs (community health workers) was established throughout the surrounding villages to serve as a link with the community, and to provide directly observed treatment (DOT).

RESULTS

In the first year of programme scale-up, over 8000 patients were followed for HIV, and over 1050 were treated with DOT HAART. Adherence to HAART was very high, and clinical outcomes were excellent: all patients responded with weight gain and improved functional capacity, and fewer than 5% required medication changes due to side effects. Viral load was tested among a subset of patients showing that 86% had undetectable viral loads.

CONCLUSION

Community-based care of AIDS has been highly effective in rural Haiti. With more international financial support for HIV/AIDS treatment in resource-limited settings, there should be no barriers to access to life-saving HAART for those who need it most.

摘要

目的

扩大一个成功的艾滋病毒/艾滋病治疗项目规模,为海地农村整个中央省(人口55万)提供全面护理,从而证明在资源有限的环境中基于社区的艾滋病毒治疗是可行且高效的,并成为可供其他地区复制的成功模式。

参与者

在海地农村中央省,为所有前来寻求治疗的人免费提供全面的艾滋病毒和结核病治疗。所有符合临床入组标准的人都接受高效抗逆转录病毒疗法(HAART)治疗。

干预措施

第一年在四个地点开展了一个综合项目,提供艾滋病毒、结核病、性传播疾病的治疗与预防以及妇女健康服务,同时提供HAART。在每个地点,医疗设施进行了翻新,根据需要招聘了更多工作人员,并在周边村庄建立了一个由社区卫生工作者组成的网络,作为与社区的联系纽带,并提供直接观察治疗(DOT)。

结果

在项目扩大规模的第一年,对8000多名艾滋病毒患者进行了跟踪,超过1050人接受了DOT HAART治疗。HAART的依从性非常高,临床效果极佳:所有患者体重增加,功能能力改善,因副作用需要更换药物的患者不到5%。对一部分患者进行了病毒载量检测,结果显示86%的患者病毒载量检测不到。

结论

在海地农村,基于社区的艾滋病护理非常有效。如果在资源有限的环境中能获得更多国际资金用于艾滋病毒/艾滋病治疗,那么对于最需要的人来说,获取挽救生命的HAART应该没有障碍。

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