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[后路减压与内固定在脊柱恶性肿瘤治疗中的意义]

[Significance of dorsal decompression and instrumentation in the treatment of spinal malignancies].

作者信息

Rompe J D, Hopf C, Heine J

机构信息

Orthopädische Universitäts- und Poliklinik Mainz.

出版信息

Z Orthop Ihre Grenzgeb. 1992 Jan-Feb;130(1):51-8. doi: 10.1055/s-2008-1039512.

DOI:10.1055/s-2008-1039512
PMID:1532272
Abstract

From 1986 to 1990 50 patients with increasing spinal instability due to pathologic fractures of one or more vertebrae were operated in the Orthopedic Department of Mainz University Hospital. In the course of 57 operations anterior decompression and stabilization were performed 3 times, whereas dorsal spondylodesis was done with Cotrel-Dubousset's instrumentation (CDI) 32 times, with Luque's 7 times and with Harrington's 1 time; a combination of CDI and Luque was chosen in 2 cases, a combination of Harrington and Luque in 1 case. 3 times a single-stage combination and 4 times a two-stage combination of ventral and dorsal stabilization was used. The application of the CDI required no postoperative external support. 35 patients suffered from major neurologic deficits preoperatively--among them 11 from a complete and 6 from an incomplete paraparesis--which made spinal cord decompression necessary in advance of the dorsal stabilization. Of these, 16 improved significantly; however, deterioration of the neurologic status occurred in 4 cases with a paraparesis in 3 of them. Survival time postoperatively was approximately 13 months in 27 patients. 9 of these died within half a year after the operative intervention. Failure of fixation as a result of tumor lesion was found in 2 cases of CDI procedure and in 1 case of the Harrington instrumentation. All required a revisional operation. 3 patients developed a radiologic lysis of methylmethacrylate implants fixed by an anterior procedure. Posterior decompression and stabilization render possible resolution of spine pain as well as restoration of mobility until a few days before exitus letalis without restricting adjuvant radio- or chemotherapy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1986年至1990年期间,美因茨大学医院骨科对50例因一个或多个椎体病理性骨折导致脊柱不稳定加重的患者进行了手术。在57次手术过程中,进行了3次前路减压和稳定手术,而采用Cotrel-Dubousset器械(CDI)进行后路脊柱融合术32次,采用Luque器械7次,采用Harrington器械1次;2例采用CDI和Luque联合,1例采用Harrington和Luque联合。3次采用腹侧和背侧稳定的单阶段联合,4次采用两阶段联合。应用CDI术后无需外部支撑。35例患者术前存在严重神经功能缺损,其中11例完全性和6例不完全性截瘫,因此在进行背侧稳定之前需要先行脊髓减压。其中16例有明显改善;然而,4例发生神经功能状态恶化,其中3例为截瘫。27例患者术后生存时间约为13个月。其中9例在手术干预后半年内死亡。2例CDI手术和1例Harrington器械固定出现因肿瘤病变导致的内固定失败。均需要进行翻修手术。3例患者出现前路固定的甲基丙烯酸甲酯植入物的影像学溶解。后路减压和稳定可在濒死期前数天缓解脊柱疼痛并恢复活动能力,且不限制辅助放疗或化疗。(摘要截短至250字)

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1
[Significance of dorsal decompression and instrumentation in the treatment of spinal malignancies].[后路减压与内固定在脊柱恶性肿瘤治疗中的意义]
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引用本文的文献

1
Metastatic spinal cord compression--options for surgical treatment.转移性脊髓压迫症——外科治疗选择
Acta Neurochir (Wien). 1993;123(3-4):135-40. doi: 10.1007/BF01401869.
2
[Experiences with combined interventions on the lumbar spine].
Unfallchirurgie. 1995 Aug;21(4):167-74. doi: 10.1007/BF02588696.