Yusa T, Sasara T, Shimabukuro T, Higa Y
Department of Anesthesiology, Faculty of Medicine, University of the Ryukyus, Okinawa.
Masui. 1992 Feb;41(2):232-7.
Arterial as well as end-tidal PCO2 (PaCO2, PetCO2), and arterial to end-tidal PCO2 difference (P(a-ET)CO2) were studied in 16 ASA-I patients anesthetized for laparoscopy under controlled ventilation. Using constant ventilation throughout the procedure, PaCO2 and PetCO2 increased significantly (P less than 0.01) to the maximum level (about 10 mmHg above the control level) within 22 min after CO2 insufflation, along with significant increase in mean arterial pressure and heart rate. There was a statistically significant correlation between PaCO2 and PetCO2 at the time of control (before surgery), at the time of maximum PetCO2 and 30 to 60 min after CO2 insufflation (P less than 0.01). Although mean P(a-ET)CO2 remained relatively constant during the procedure, a statistically significant correlation between PaCO2 and P(a-ET)CO2 was found at the time of maximum PetCO2 after CO2 insufflation (r = 0.71, P less than 0.01). These results suggest that when PvCO2 is increasing by CO2 insufflation, P(a-ET)CO2 depend on relative ventilation efficacy.
对16例接受腹腔镜手术、在控制通气下麻醉的美国麻醉医师协会（ASA）I级患者，研究了动脉血及呼气末二氧化碳分压（PaCO2、PetCO2）以及动脉血与呼气末二氧化碳分压差（P(a-ET)CO2）。在整个手术过程中采用恒定通气，二氧化碳气腹后22分钟内，PaCO2和PetCO2显著升高（P<0.01）至最高水平（比对照水平高约10 mmHg），同时平均动脉压和心率显著升高。在对照时（手术前）、PetCO2最高时以及二氧化碳气腹后30至60分钟时，PaCO2和PetCO2之间存在统计学显著相关性（P<0.01）。尽管在手术过程中平均P(a-ET)CO2保持相对恒定，但在二氧化碳气腹后PetCO2最高时，发现PaCO2与P(a-ET)CO2之间存在统计学显著相关性（r = 0.71，P<0.01）。这些结果表明，当因二氧化碳气腹导致PvCO2升高时，P(a-ET)CO2取决于相对通气效率。
