[脾破裂与抗凝治疗]

[Splenic rupture and anticoagulant therapy].

作者信息

Badaoui R, Chebboubi K, Delmas J, Jakobina S, Mahjoub Y, Riboulot M

机构信息

Département d'anesthésie-réanimation B, CHU d'Amiens, place Victor-Pauchet, 80054 Amiens, France.

出版信息

Ann Fr Anesth Reanim. 2004 Jul;23(7):748-50. doi: 10.1016/j.annfar.2004.04.018.

DOI:10.1016/j.annfar.2004.04.018

PMID:15324967

Abstract

Splenic rupture associated with anticoagulant therapy is a rare entity. We report a case of spontaneous splenic rupture in a 62-year-old man who was treated by acenocoumarol orally after an aortic-valve replacement. Unrecognised, minor trauma may lead to splenic haemorrhage in patients receiving anticoagulant therapy. The symptoms and signs may mimic those of acute myocardial infarction and cardiogenic shock. Early diagnosis is essential. Reversal of the anticoagulant and emergent splenectomy are the treatments of choice.

摘要

抗凝治疗相关的脾破裂是一种罕见的情况。我们报告一例62岁男性自发性脾破裂病例，该患者在主动脉瓣置换术后接受口服醋硝香豆素治疗。在接受抗凝治疗的患者中，未被识别的轻微创伤可能导致脾出血。症状和体征可能类似于急性心肌梗死和心源性休克。早期诊断至关重要。逆转抗凝作用并紧急行脾切除术是首选的治疗方法。