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白色念珠菌骨髓炎:病例报告及文献综述

Candida albicans osteomyelitis: case report and literature review.

作者信息

Arias Félix, Mata-Essayag Sofía, Landaeta María E, Capriles Claudia Hartung de, Pérez Celina, Núñez María J, Carvajal Ana, Silva Marisela

机构信息

Servicio de Enfermedades Infecciosas del Adulto, Hospital Universitario de Caracas, Venezuela.

出版信息

Int J Infect Dis. 2004 Sep;8(5):307-14. doi: 10.1016/j.ijid.2003.12.006.

Abstract

OBJECTIVE

Osteomyelitis due to Candida species is an unusual but recognized entity. However, with the increasing occurrence of factors predisposing to candidemia and invasive candidiasis, candidal osteomyelitis is being diagnosed more frequently. An unusual case of Candida albicans osteomyelitis is reported here, along with a review of the published literature on previously reported cases of this disease.

METHODS

Report of the case and literature review.

RESULTS

In this case, Candida albicans was isolated from the talus; however, the diagnosis was made after several cultures were performed. Only one other case of Candida osteomyelitis located in foot bones was found in the review.

CONCLUSIONS

It is thought that this is the first case reported in Venezuela, and only the second in international literature.

摘要

目的

念珠菌属引起的骨髓炎是一种罕见但已被认知的疾病。然而,随着易患念珠菌血症和侵袭性念珠菌病的因素日益增多,念珠菌性骨髓炎的诊断也越来越频繁。本文报告了一例不寻常的白色念珠菌骨髓炎病例,并对已发表的关于该疾病既往报道病例的文献进行了综述。

方法

病例报告及文献综述。

结果

在该病例中,从距骨分离出白色念珠菌;然而,在进行了多次培养后才作出诊断。综述中仅发现另一例位于足部骨骼的念珠菌性骨髓炎病例。

结论

据认为,这是委内瑞拉报道的首例病例,也是国际文献中的第二例。

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