Muttalib M, Tisdall M, Scawn R, Shousha S, Cummins R S, Sinnett H D
Department of Breast Surgery, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK.
Breast. 2004 Aug;13(4):307-15. doi: 10.1016/j.breast.2004.02.005.
Recent advances in digital imaging have made Faxitron microradiography an attractive alternative to intra-operative conventional specimen radiography (CSR) for the excision of wire-localized breast lesions. Faxitron specimen analysis time, usefulness of digital image manipulation and re-excision rates were evaluated in comparison to CSR in 299 consecutive wire-localized excisions for mammographically suspicious non-palpable breast lesions (172 procedures with Faxitron, 127 with CSR) in a non-randomized study. The corresponding mean operation times were 34.7 vs. 42.7 min and the respective re-excision rates were 19.8% vs. 31.5% (no significant difference on chi analysis P < 0.1). Faxitron digital image manipulation led to cavity biopsies in 50% (60/121) of the cancer excisions. In 19 of these (16%), histological excision margins were converted from incomplete to complete. The shorter Faxitron mean operating time enables an additional wire-localized operation per theatre list. Digital imaging guides the surgeon for additional cavity biopsies, resulting in re-excision rates as good as CSR.
数字成像技术的最新进展使 Faxitron 微放射成像成为术中传统标本放射成像（CSR）之外，用于切除乳腺导丝定位病变的一种有吸引力的替代方法。在一项非随机研究中，对 299 例连续的乳腺 X 线摄影可疑的不可触及乳腺病变的导丝定位切除术（172 例使用 Faxitron，127 例使用 CSR）进行了评估，比较了 Faxitron 的标本分析时间、数字图像处理的有用性和再次切除率。相应的平均手术时间分别为 34.7 分钟和 42.7 分钟，各自的再次切除率分别为 19.8%和 31.5%（卡方分析 P < 0.1，无显著差异）。Faxitron 数字图像处理在 50%（60/121）的癌症切除术中实现了切缘活检。其中 19 例（16%）的组织学切除切缘从不完整变为完整。Faxitron 平均手术时间较短，使得每个手术安排能够额外进行一次导丝定位手术。数字成像为外科医生进行额外的切缘活检提供了指导，再次切除率与 CSR 相当。
