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脉络膜血管瘤的碘-125敷贴放射治疗。

Iodine-125 plaque radiotherapy of choroidal hemangioma.

作者信息

Fujimoto L T, Anderson S F

机构信息

Optometry Section, Las Vegas VA Outpatient Clinic, Las Vegas, Nevada, USA.

出版信息

Optometry. 2000 Jul;71(7):431-8.

Abstract

BACKGROUND

Circumscribed choroidal hemangioma (CCH) is a benign vascular tumor that is not associated with systemic abnormalities and its pathogenesis is unknown. Most choroidal hemangiomas remain stable in size, and treatment is periodic observation unless complicated by an overlying serous retinal detachment.

CASE REPORT

A 43-year-old white man came to our clinic reporting decreased vision in the left eye for 1 year. On funduscopic evaluation, a large elevated nonpigmented red-orange lesion, just temporal to the fovea of the left eye, was observed with surrounding areas of subretinal fluid. On the basis of findings obtained through ophthalmoscopy, fluorescein angiography, and ultrasonography, the patient was diagnosed with a circumscribed choroidal hemangioma. Treatment of the CCH was with iodine-125 plaque radiotherapy, which significantly reduced the tumor size and improved vision.

CONCLUSION

CCH is a benign vascular tumor that is characteristically nonprogressive, but in cases of vision loss caused by serous detachment of the fovea, argon laser photocoagulation or radiotherapy is the treatment of choice. Recent studies indicate that iodine-125 plaque radiotherapy is indicated for large choroidal hemangiomas involving the macula or with associated retinal detachment. The main goal of treating CCH is to preserve vision and to prevent the progression of vision loss.

摘要

背景

局限性脉络膜血管瘤(CCH)是一种良性血管肿瘤,与全身异常无关,其发病机制尚不清楚。大多数脉络膜血管瘤大小保持稳定,除非并发浆液性视网膜脱离,否则治疗方法是定期观察。

病例报告

一名43岁白人男性因左眼视力下降1年前来我院就诊。眼底检查发现,左眼黄斑颞侧有一个大的隆起性无色素红橙色病变,周围有视网膜下液。根据眼底镜检查、荧光素血管造影和超声检查结果,该患者被诊断为局限性脉络膜血管瘤。CCH的治疗采用碘-125敷贴放疗,显著缩小了肿瘤大小并改善了视力。

结论

CCH是一种良性血管肿瘤,通常不会进展,但在因黄斑浆液性脱离导致视力丧失的情况下,氩激光光凝或放疗是首选治疗方法。最近的研究表明,碘-125敷贴放疗适用于累及黄斑或伴有视网膜脱离的大型脉络膜血管瘤。治疗CCH的主要目标是保留视力并防止视力丧失进展。

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