Kubicka-Trząska Agnieszka, Kobylarz Joanna, Romanowska-Dixon Bożena
Department of Ophthalmology and Ocular Oncology, Medical College, Jagiellonian University, Kopernika Street 38, 31-501 Kraków, Poland.
Case Rep Ophthalmol Med. 2011;2011:785686. doi: 10.1155/2011/785686. Epub 2011 Sep 29.
Diffuse choroidal hemangiomas associated with Sturge-Weber syndrome (SWS) are classically treated with external beam radiotherapy (EBR), but there are a few reports usually of single cases indicating the usefulness of plaque therapy. We present our observations on two cases of diffuse choroidal hemangiomas with exudative retinal detachment associated with SWS treated with Ruthenium-106 plaque therapy. Outcomes included best-corrected visual acuity (BCVA) and regression in tumor thickness measured by ultrasonography. The initial BCVA of the affected eyes was counting fingers at 1 meter and light projection. Pretreatment tumors thickness was 3.5 mm and 4.7 mm. In a follow-up period of 18-24 months, significant reduction in thickness of choroidal hemangiomas up to 1.2 mm and 1.4 mm with prompt resolution of exudative retinal detachment was observed. BCVA achieved 20/200 and 20/400, respectively. The findings in this paper indicate that Ruthenium-106 plaque therapy is effective in treatment of diffuse choroidal hemangiomas associated with SWS.
与斯-韦综合征(SWS)相关的弥漫性脉络膜血管瘤传统上采用外照射放疗(EBR)治疗,但有一些通常为单例的报告表明敷贴疗法有用。我们介绍了两例与SWS相关的伴有渗出性视网膜脱离的弥漫性脉络膜血管瘤采用钌-106敷贴疗法治疗的观察结果。结果包括最佳矫正视力(BCVA)以及通过超声测量的肿瘤厚度的消退情况。患眼的初始BCVA为1米处数指和光感。治疗前肿瘤厚度分别为3.5毫米和4.7毫米。在18至24个月的随访期内,观察到脉络膜血管瘤厚度显著减少,分别达1.2毫米和1.4毫米,渗出性视网膜脱离迅速消退。BCVA分别达到了20/200和20/400。本文的研究结果表明,钌-106敷贴疗法在治疗与SWS相关的弥漫性脉络膜血管瘤方面是有效的。