Mor V
Brown University Center for Gerontology and Health Care Research, Providence, RI 02912.
Oncology (Williston Park). 1992 Feb;6(2 Suppl):146-52.
Increasingly, researchers studying the effects of medical treatments and health policy initiatives consider morbidity and not just mortality outcomes. Since older cancer patients are increasingly involved in chemotherapeutic and radiation therapy trials, it is important to know that commonly used quality of life measures are applicable to the aged as well as the younger population. Do older patients manifest poorer quality of life at various points in the disease course than do younger patients? We analyzed data from three studies on (1) newly diagnosed cancer patients, (2) patients on chemotherapy, and (3) advanced cancer patients regarding quality of life and compared the scores observed among older and younger individuals. After correcting for comorbidity and physical frailty, we found no quality of life differences between older and younger patients.
越来越多研究医学治疗效果和健康政策举措的研究人员开始关注发病率而非仅仅是死亡率结果。由于老年癌症患者越来越多地参与化疗和放疗试验，了解常用的生活质量衡量标准是否适用于老年人群以及年轻人群非常重要。在疾病过程的各个阶段，老年患者的生活质量是否比年轻患者更差？我们分析了三项关于（1）新诊断癌症患者、（2）化疗患者和（3）晚期癌症患者生活质量的研究数据，并比较了老年和年轻个体的得分。在校正合并症和身体虚弱因素后，我们发现老年和年轻患者在生活质量方面没有差异。
