Nour Ashraf
Department of Surgery, Menoufiya University, Shebin-el-kom, Egypt.
Breast J. 2004 Sep-Oct;10(5):388-91. doi: 10.1111/j.1075-122X.2004.21360.x.
Sentinel lymph node biopsy (SLNB) is an important surgical advance in the management of early breast cancer. Localization of the sentinel lymph node (SLN) in breast cancer and other cancer patients is widely used now utilizing isosulfan blue dye. Few alternative types of dye have been used and investigated. In a prospective study of 54 patients, methylene blue dye was used as an alternative to isosulfan blue to localize the SLN in breast cancer patients. The methylene blue dye technique was successful in 91.1% of patients after excluding the initial learning cases; the results are similar for isosulfan blue dye. This study describes methylene blue dye localization as a successful alternative to isosulfan blue dye in identifying the sentinel node in breast cancer patients. Methylene blue dye is readily available in most Egyptian institutes, with a very low cost.
前哨淋巴结活检（SLNB）是早期乳腺癌治疗中的一项重要手术进展。目前，异硫蓝染料广泛用于乳腺癌及其他癌症患者前哨淋巴结（SLN）的定位。很少有其他类型的染料被使用和研究。在一项对54例患者的前瞻性研究中，亚甲蓝染料被用作异硫蓝的替代物来定位乳腺癌患者的SLN。排除初始学习病例后，亚甲蓝染料技术在91.1%的患者中取得成功；异硫蓝染料的结果与之相似。本研究描述了亚甲蓝染料定位是识别乳腺癌患者前哨淋巴结的一种成功的异硫蓝染料替代方法。亚甲蓝染料在大多数埃及机构中很容易获得，成本非常低。
