Leszczyszyn David J, Pellock John M
Division of Child Neurology, Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298-0211, USA.
Am J Electroneurodiagnostic Technol. 2004 Jun;44(2):75-94.
Five new antiepileptic drugs (AEDs) have been approved in the last five years and several new formulations and new dose strengths for both the classical and newer agents exist. Patients arriving for neurodiagnostic studies are often on complex regimens with medications being weaned and new agents being added. All technologists need a working knowledge of the known mechanisms and indications for these drugs in addition to an understanding of their potential adverse effects. Fortunately the latter problems are limited in this recent generation of drugs and their broad spectrum of action is leading to improved seizure control and better quality of life for our patients.
在过去五年中，已有五种新型抗癫痫药物（AEDs）获批，并且经典药物和新型药物都有几种新的制剂和新的剂量规格。前来进行神经诊断研究的患者通常采用复杂的治疗方案，药物逐渐减量，同时添加新的药物。除了了解这些药物的潜在不良反应外，所有技术人员都需要掌握这些药物已知的作用机制和适应证方面的实用知识。幸运的是，在这一代新药中，后一个问题较为有限，而且它们广泛的作用谱正在改善癫痫控制情况，并提高我们患者的生活质量。
