Morrell Martha J
Department of Neurology, The Neurological Institute, Columbia University, New York, New York 10032, USA.
Semin Neurol. 2002 Sep;22(3):247-58. doi: 10.1055/s-2002-36645.
Epilepsy is one of the most common neurological conditions encountered worldwide. The development of newer antiepileptic drugs (AEDs) has expanded over recent years, and the use of such drugs for indications other than epilepsy has also broadened. These factors insure that the majority of health care providers will be using an increasing number of AEDs in the care of their patients. Contained herein is a review of the mechanism of action of AEDs, individual drugs and their potential drug interactions, and general principles to guide the clinician in selection, implementation, and long-term monitoring of AEDs.
癫痫是全球最常见的神经系统疾病之一。近年来，新型抗癫痫药物（AEDs）不断涌现，这类药物在癫痫以外适应症方面的应用也日益广泛。这些因素使得大多数医疗保健人员在治疗患者时会使用越来越多的抗癫痫药物。本文将对抗癫痫药物的作用机制、各类药物及其潜在的药物相互作用进行综述，并阐述指导临床医生选择、使用及长期监测抗癫痫药物的一般原则。
