Myrick Hugh, Malcolm Robert, Taylor Brent, LaRowe Steven
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Ann Clin Psychiatry. 2004 Apr-Jun;16(2):101-9. doi: 10.1080/10401230490453743.
Modafinil is an agent that is frequently used in the treatment of narcolepsy. More recently it has been used in the treatment of a variety of psychiatric, neurological, and medical illnesses. Due to its ability to improve wakefulness, modafinil has been viewed as a stimulant. Based on the potential for modafinil to become widely used in a variety of syndromes and settings, evidence from preclinical in vitro and in vivo studies, human laboratory studies, and post-marketing experiences examining the potential abuse liability of modafinil were reviewed. Initial evidence suggests that modafinil has limited potential for large-scale abuse.
莫达非尼是一种常用于治疗发作性睡病的药物。最近，它已被用于治疗多种精神、神经和医学疾病。由于其能够改善清醒状态，莫达非尼被视为一种兴奋剂。基于莫达非尼可能在多种综合征和环境中广泛使用的可能性，我们回顾了临床前体外和体内研究、人体实验室研究以及上市后有关莫达非尼潜在滥用可能性的经验证据。初步证据表明，莫达非尼大规模滥用的可能性有限。
