[Human blood vessels created with tissue engineering].

作者信息

Stoclet Jean-Claude, Laflamme Karina, Auger François A, Germain Lucie

机构信息

Laboratoire de pharmacologie et physicochimie des interactions cellulaires et moléculaires, UMR Cnrs 7034, Faculté de pharmacie, BP 24, 74, route du Rhin, 67401 Illkirch, France.

出版信息

Med Sci (Paris). 2004 Jun-Jul;20(6-7):675-8. doi: 10.1051/medsci/2004206-7675.

DOI:10.1051/medsci/2004206-7675

PMID:15329818

Abstract

Progress in tissue engineering now allows the recreation of functional blood vessels from cultured human vascular cells. When reconstructed under specific conditions, their structure, mechanical properties and function (especially vasomotricity) allow them to be used as human models for studying the biology and pharmacology of blood vessels. These models may help to circumvent the limitations in the obtention and use of native human blood vessels for experimental purpose.

摘要