新西兰男性饮食中的种族差异及其与前列腺疾病临床指标的关联。

Ethnic differences in diet and associations with clinical markers of prostate disease in New Zealand men.

作者信息

Harris Anna, Gray Marion A, Slaney David P, Turley Maria L, Fowles Jefferson R, Weinstein Philip

机构信息

Department of Public Health, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand.

出版信息

Anticancer Res. 2004 Jul-Aug;24(4):2551-6.

PMID:15330213

Abstract

OBJECTIVE

To examine ethnic differences in diet and dietary associations with clinical markers of prostate disease in New Zealand men.

MATERIALS AND METHODS

A total of 1031 males (616 New Zealand European, 230 Maori and 185 Pacific Islands) aged 40-69 years, with no history of prostate cancer, completed a questionnaire covering diet. A serum prostate specific antigen (PSA) blood analysis was also undertaken. Regression models were developed to examine the ethnic-specific levels of selected dietary components, and their relationship with PSA and urinary symptom scores.

RESULTS

The results confirmed previously found ethnic differences in the New Zealand diet. Combined tomato intake was positively-correlated with free PSA and % free PSA (p=0.021, r=0.197 and p=0.011, r=0.096 respectively). Beer intake was negatively-correlated with total PSA (p=0.028, r=-0.071) and free PSA (p=0.004, r=-0.094).

CONCLUSION

Ethnic differences found in the consumption of foods (associated with prostate cancer) highlight the possible importance of dietary interactions for ethnic prostate cancer risk. Associations between specific foods and PSA warrant further investigation.

摘要

目的

研究新西兰男性在饮食方面的种族差异以及饮食与前列腺疾病临床指标之间的关联。

材料与方法

共有1031名年龄在40至69岁之间、无前列腺癌病史的男性（616名新西兰欧洲人、230名毛利人和185名太平洋岛民）完成了一份关于饮食的问卷。同时还进行了血清前列腺特异性抗原（PSA）血液分析。建立回归模型以研究特定饮食成分的种族特异性水平，及其与PSA和尿路症状评分的关系。

结果

结果证实了此前发现的新西兰饮食中的种族差异。番茄摄入量与游离PSA和游离PSA百分比呈正相关（分别为p = 0.021，r = 0.197和p = 0.011，r = 0.096）。啤酒摄入量与总PSA（p = 0.028，r = -0.071）和游离PSA（p = 0.004，r = -0.094）呈负相关。