防御素：脊椎动物的抗菌肽。

Defensins: antimicrobial peptides of vertebrates.

作者信息

Ganz Tomas

机构信息

CHS 37-055, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1690, USA.

出版信息

C R Biol. 2004 Jun;327(6):539-49. doi: 10.1016/j.crvi.2003.12.007.

DOI:10.1016/j.crvi.2003.12.007

PMID:15330253

Abstract

This review, based on my presentation at the French Academy of Sciences on May 19, 2003, describes recent progress in the study of antimicrobial peptides, mediators of innate immunity in plants and animals. The main focus is on vertebrate defensins, a family of cysteine-rich antimicrobial peptides abundantly represented in human cells and tissues.

摘要

这篇综述基于我于2003年5月19日在法国科学院的演讲，描述了抗菌肽（动植物先天免疫的介质）研究的最新进展。主要聚焦于脊椎动物防御素，这是一类富含半胱氨酸的抗菌肽家族，在人类细胞和组织中大量存在。