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[存在前壁半阻滞时左心室肥厚的心电图诊断是否可行?]

[Is electrocardiographic diagnosis of left ventricular hypertrophy possible in the presence of an anterior hemiblock?].

作者信息

Schläpfer J, Jaussi A, Jaeger M

机构信息

Policlinique médicale universitaire, Lausanne.

出版信息

Schweiz Med Wochenschr. 1992 Apr 11;122(15):554-8.

PMID:1533053
Abstract

The electrocardiographic diagnosis of left ventricular hypertrophy is often difficult because it is based on a large number of criteria which, even if taken on their own or as "scoring systems", have a poor sensitivity ranging from 10 to 60%. Some authors have shown that the diagnosis is easier--though at first sight this seems paradoxical--in the presence of altered ventricular depolarization. To verify this statement in the case of left anterior fascicular block, we tested the value of six different indices for the detection of left ventricular hypertrophy. We analyzed 100 patients with left anterior fascicular block and compared the six electrocardiographic indices with the echocardiographic reference method, using the formula of the Penn convention, to establish the left ventricular mass. The best index of the six was that of Gertsch: [S3+ (R+S) maximal precordial] greater than or equal to 30 mm. Its sensitivity was 74%, its specificity 69%, its positive predictive value 79% and its negative predictive value 63%. The other tested indices had a sensitivity of less than 45% with a specificity of more than 80%. Furthermore, Gertsch's index was of equal value in confirming the increased left ventricular mass due either to concentric hypertrophy or to dilated cardiomyopathy. This study therefore confirms that electrocardiographic diagnosis of left ventricular hypertrophy is even easier in the presence of left anterior fascicular block than in absence of altered ventricular depolarization. This result is of practical interest, the incidence of left anterior fascicular block being 1 to 5% in the general population and as high as 30% after the age of 80.

摘要

左心室肥大的心电图诊断往往很困难,因为它基于大量标准,即使单独采用这些标准或作为“评分系统”,其敏感性也很差,仅为10%至60%。一些作者表明,在心室去极化改变的情况下,诊断更容易——尽管乍一看这似乎自相矛盾。为了在左前分支阻滞的情况下验证这一说法,我们测试了六种不同指标检测左心室肥大的价值。我们分析了100例左前分支阻滞患者,并将这六种心电图指标与超声心动图参考方法进行比较,采用宾夕法尼亚公约公式确定左心室质量。这六种指标中最佳的是格奇指标:[S3 +(R + S)胸前导联最大值]≥30mm。其敏感性为74%,特异性为69%,阳性预测值为79%,阴性预测值为63%。其他测试指标的敏感性低于45%,特异性高于80%。此外,格奇指标在确认由同心性肥大或扩张型心肌病导致的左心室质量增加方面具有同等价值。因此,本研究证实,存在左前分支阻滞时左心室肥大的心电图诊断比不存在心室去极化改变时更容易。这一结果具有实际意义,因为左前分支阻滞在普通人群中的发生率为1%至5%,在80岁以后高达30%。

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