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局部炎症作为偏头痛和紧张型头痛的介质。

Local inflammation as a mediator of migraine and tension-type headache.

作者信息

Friedman Mark H

机构信息

New York Medical College, Valhalla, USA.

出版信息

Headache. 2004 Sep;44(8):767-71. doi: 10.1111/j.1526-4610.2004.04143.x.

DOI:10.1111/j.1526-4610.2004.04143.x
PMID:15330822
Abstract

OBJECTIVE

To demonstrate the relationship of migraine and tension-type headache to a localized maxillary gingival inflammation.

BACKGROUND

Intraoral tenderness has been observed consistently in the most common types of primary headache disorders. The laterality and degree of tenderness is related to laterality and severity of reported symptoms, both during headache and in the interictal state.

METHODS

Bilateral posterior maxillary palpation and local temperature recordings were performed during unilateral migraine and tension-type headache. Local anti-inflammatory techniques, ie, local chilling and a topical anti-inflammatory gel, were used in these tender areas in episodic migraine and tension-type headache patients.

RESULTS

Ipsilateral intraoral tenderness and increased local temperature were consistently observed during unilateral migraine and tension-type headache, suggesting local inflammation. Intraoral chilling and topical application of a nonsteroidal anti-inflammatory drug were highly effective for the treatment of migraine and tension-type headache, both in the acute phase and for headache prevention.

CONCLUSION

These results suggest that a local intraoral inflammation may be associated with the pathogenesis of these common headaches.

摘要

目的

证明偏头痛和紧张型头痛与局限性上颌牙龈炎症之间的关系。

背景

在最常见的原发性头痛疾病中,口腔内压痛一直被观察到。压痛的侧别和程度与头痛发作期间及发作间期报告症状的侧别和严重程度相关。

方法

在单侧偏头痛和紧张型头痛发作期间,进行双侧上颌后部触诊和局部温度记录。在发作性偏头痛和紧张型头痛患者的这些压痛区域,采用局部抗炎技术,即局部冷敷和外用抗炎凝胶。

结果

在单侧偏头痛和紧张型头痛发作期间,始终观察到同侧口腔内压痛和局部温度升高,提示局部炎症。口腔内冷敷和外用非甾体抗炎药对偏头痛和紧张型头痛的治疗在急性期和预防头痛方面都非常有效。

结论

这些结果表明,局部口腔炎症可能与这些常见头痛的发病机制有关。

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