Faculty of Dentistry, Department of Endodontics, Mersin University, Private Practice, Mersin, Turkey.
Faculty of Dentistry, Department of Prosthodontics, Mersin University, Mersin, Turkey.
BMC Oral Health. 2024 Sep 4;24(1):1043. doi: 10.1186/s12903-024-04705-9.
Migraine is one of the most common primary headaches worldwide, while toothache is the most common pain in the orofacial region. The association of migraine pain, and oral pain is unknown. This study aims to investigate the association between migraine and dental and gingival pain with the presence of allodynia.
A questionnaire comprising demographic data with the ID-Migraine (IDM) tool, an Allodynia Symptom Checklist (ASC), and inquiries about pain and sensitivity in the teeth and gums during migraine attacks was administered to the participants and 762 responded the survey. The study classified participants based on the ASC, and the relationship between allodynia and pain/sensitivity in the teeth and/or gums during migraine attacks was analyzed. The statistical analyses utilized Chi-square tests and the Fisher-Exact test.
Among 762 migraine patients, 430 (56.44%) were classified as allodynia (+), while 332 (43.56%) were classified as allodynia (-) (p < 0.001). Additionally, 285 participants (37.5%) reported experiencing pain and sensitivity in the teeth and gums during migraine attacks, with a significant relationship observed between allodynia and pain/sensitivity in the teeth and/or gums during migraine attacks (p < 0.001).
The findings of this study have important clinical implications. For migraine patients who are non-allodynic, the presence of pain and sensitivity in their teeth and gums during migraine attacks may indicate underlying dental diseases or the need for dental treatment especially root canal treatment. However, for allodynic patients, such symptoms may not necessarily indicate the presence of dental diseases or the need for dental treatment especially root canal treatment. These results underscore the significance of considering the presence of allodynia in the assessment and management of oral symptoms during migraine attacks.
偏头痛是全球最常见的原发性头痛之一，而牙痛是口腔颌面部最常见的疼痛。偏头痛疼痛与口腔疼痛之间的关联尚不清楚。本研究旨在调查偏头痛与牙齿和牙龈疼痛以及痛觉过敏之间的关联。
向参与者发放了一份包含人口统计学数据的问卷，其中包括 ID-Migraine（IDM）工具、痛觉过敏症状检查表（ASC）以及偏头痛发作期间牙齿和牙龈疼痛和敏感性的询问。共有 762 名参与者对调查做出了回应。本研究根据 ASC 对参与者进行分类，并分析偏头痛发作期间痛觉过敏与牙齿和/或牙龈疼痛/敏感性之间的关系。统计分析采用卡方检验和 Fisher 精确检验。
在 762 名偏头痛患者中，430 名（56.44%）被归类为痛觉过敏（+），332 名（43.56%）被归类为痛觉过敏（-）（p<0.001）。此外，285 名参与者（37.5%）报告在偏头痛发作期间出现牙齿和牙龈疼痛和敏感性，痛觉过敏与偏头痛发作期间牙齿和/或牙龈疼痛/敏感性之间存在显著关系（p<0.001）。
本研究的结果具有重要的临床意义。对于非痛觉过敏的偏头痛患者，偏头痛发作期间牙齿和牙龈疼痛和敏感性的存在可能表明存在潜在的牙齿疾病或需要进行牙科治疗，特别是根管治疗。然而，对于痛觉过敏的患者，这些症状不一定表明存在牙齿疾病或需要进行牙科治疗，特别是根管治疗。这些结果强调了在评估和管理偏头痛发作期间口腔症状时考虑痛觉过敏的重要性。
