Voigt K, Marquardt B
Rofo. 1979 Jan;130(1):89-94. doi: 10.1055/s-0029-1231230.
The angiographic diagnostic features of concordant tumors of the posterior fossa in monozygotic twins are described. In both cotwins cranio-spinal subependymomas were found which had grown through the foramen magnum and reached from the fourth ventricle down to the second cervical vertebra. Thereby, the conformity of the clinical mainifestation, symptomotology and the course of the disease, the localisation and extent of the tumors as well as the neuroradiologic findings and the histologic features of the tumors were particularly striking. After a review and critical summary of the few cases of concordant affections with brain tumors in identical twins published in the literature at present our couple is discussed under the question of the possible influence of genetic factors or a hereditary disposition on the development of cerebral tumors.