Clarenbach P, Kleihues P, Metzel E, Dichgans J
J Neurosurg. 1979 May;50(5):655-9. doi: 10.3171/jns.1979.50.5.0655.
At the age of 22 years, identical twin brothers simultaneously developed symptoms of intracranial pressure. Radiological investigation revealed cerebellar midline tumors with occlusive hydrocephalus of the third and lateral ventricles. At operation, subependymomas with identical histological features were found in the fourth ventricle in both twins. This is the first report of subependymomas in identical twins. The clinical data suggest that this tumor type is of maldevelopmental origin.
22岁时，一对同卵双胞胎兄弟同时出现颅内压症状。影像学检查发现小脑中线肿瘤伴第三和侧脑室梗阻性脑积水。手术中，在双胞胎的第四脑室均发现具有相同组织学特征的室管膜下瘤。这是同卵双胞胎中室管膜下瘤的首例报告。临床资料表明这种肿瘤类型起源于发育异常。
