Touloupidis S, Fatles G, Rombis V, Papathanasiou A, Balaxis E
Department of Urology, Democritus Thrace University, Alexandroupolis, Greece.
Urol Int. 2004;73(2):169-72. doi: 10.1159/000079699.
The experience of our department on the treatment of solitary simple kidney cysts with continuous percutaneous drainage for 24 h and instillation of pure alcohol as a sclerotic agent is reported. The results are compared with those of previous years when the treatment consisted of percutaneous drainage and injection of pure alcohol.
During the period 1992-2001, 252 patients (136 male, 116 female; aged 22-74 years) were treated at our department, and all had a solitary kidney cyst. They were treated by percutaneous drainage and then injection of pure alcohol for 20 min via a nephrostomy tube (which remained in position for 24 h). The mean follow-up period was 5 years. This cohort of patients was compared to another one of 238 patients who were treated with a previous method (126 male, 124 female; aged 28-79 years, mean 59 years).
In 71% of the patients the symptoms and the cyst both disappeared, in 22% there was no significant recurrence (i.e. cyst diameter <5 cm), and the remaining 7% presented significant recurrence (i.e. cyst diameter >5 cm). Most of the latter cases were treated again using the same method. Of the 73 patients with impaired kidney function, in 61 (83%) this appeared to have improved as a result of our treatment. Of the 61 patients with hypertension, in 29 (47%) this appeared to have improved. There was only 1 case with complications, which presented purulence of the cyst that required open surgery. In previous case series, which were treated with percutaneous drainage and injection of pure alcohol just after the puncture of the cyst--without continuous drainage of the cyst for 24 h--only 10% of the patients had no recurrence, 30% had no significant recurrence (volume of the cyst <20% of the pre-operative volume), and 60% of the patients had significant recurrence (volume of the cyst >20% of the pre-operative volume).
Percutaneous drainage of solitary kidney cysts for 24 h followed by injection of pure alcohol, as a sclerotic agent, is an effective therapeutic method with only a few complications. It was therefore considered being the proffered method for the treatment of solitary kidney cysts.
报告我科采用经皮连续引流24小时并注入纯酒精作为硬化剂治疗单纯性孤立肾囊肿的经验,并将结果与前几年采用经皮引流并注射纯酒精的治疗结果进行比较。
1992年至2001年期间,我科共治疗了252例患者(男136例,女116例;年龄22至74岁),均为孤立肾囊肿患者。采用经皮引流,然后通过肾造瘘管注入纯酒精20分钟(肾造瘘管留置24小时)。平均随访期为5年。将这组患者与另一组238例采用先前方法治疗的患者进行比较(男126例,女124例;年龄28至79岁,平均59岁)。
71%的患者症状和囊肿均消失,22%的患者无明显复发(即囊肿直径<5 cm),其余7%的患者出现明显复发(即囊肿直径>5 cm)。后者大多数病例再次采用相同方法治疗。73例肾功能受损的患者中,61例(83%)经治疗后肾功能似乎有所改善。61例高血压患者中,29例(47%)经治疗后高血压似乎有所改善。仅1例出现并发症,表现为囊肿化脓,需要进行开放手术。在先前的病例系列中,囊肿穿刺后仅进行经皮引流并注射纯酒精,而不进行囊肿连续引流24小时,只有10%的患者无复发,30%的患者无明显复发(囊肿体积<术前体积的20%),60%的患者出现明显复发(囊肿体积>术前体积的20%)。
经皮引流孤立肾囊肿24小时后注入纯酒精作为硬化剂是一种有效的治疗方法,并发症较少。因此,它被认为是治疗孤立肾囊肿的首选方法。