Mohsen Tarek, Gomha Mohamed A
Department of Radiology, Mansoura Urology and Nephrology Center, Mansoura University, Egypt.
BJU Int. 2005 Dec;96(9):1369-72. doi: 10.1111/j.1464-410X.2005.05851.x.
To report our experience with the use of 95% ethanol as sclerotherapy for symptomatic simple renal cysts.
Sixty patients with 64 symptomatic simple renal cysts were treated by ultrasonography (US)-guided percutaneous aspiration and injection of 95% ethanol (31 men and 29 women, mean age 46 years, SD 22). The main presentation was renal pain in 34 patients, renal mass in nine, hypertension in 11 and haematuria in six; 24 cysts were on the right, 32 on the left and four bilateral. Patients were evaluated after 1 month and then every 6 months by clinical assessment, US and intravenous urography. Success was defined as complete when there was total ablation of the cyst and partial when there was a recurrence of less than half the original cyst volume with the resolution of symptoms. Failure was defined as the recurrence of more than half of cyst volume and/or persistent symptoms.
After aspiration and ethanol sclerotherapy, there was microscopic haematuria in two patients and low-grade fever (<38.3 degrees C) in two, but no major complications. During a mean (range) follow-up of 19 (14-40) months there was complete cyst ablation in 54 cysts and partial resolution in 10. Pain disappeared or was much improved in all patients. After cyst ablation hypertension was well controlled with no medication in all 11 hypertensive patients and haematuria disappeared in all six affected patients.
Ethanol sclerotherapy for symptomatic simple renal cysts is simple, minimally invasive and highly effective. We recommend it as the first therapeutic option in these patients.
报告我们使用95%乙醇对有症状的单纯性肾囊肿进行硬化治疗的经验。
60例患有64个有症状的单纯性肾囊肿的患者接受了超声引导下经皮穿刺抽吸并注入95%乙醇的治疗(31例男性和29例女性,平均年龄46岁,标准差22)。主要表现为34例患者有肾区疼痛,9例有肾肿块,11例有高血压,6例有血尿;24个囊肿在右侧,32个在左侧,4个为双侧性。患者在1个月后进行评估,然后每6个月通过临床评估、超声和静脉肾盂造影进行评估。成功定义为囊肿完全消融,部分成功定义为囊肿复发小于原囊肿体积的一半且症状缓解。失败定义为囊肿体积复发超过一半和/或症状持续。
抽吸和乙醇硬化治疗后,2例患者出现镜下血尿,2例出现低热(<38.3摄氏度),但无严重并发症。在平均(范围)19(14 - 40)个月的随访中,54个囊肿完全消融,10个部分缓解。所有患者的疼痛消失或明显改善。囊肿消融后,所有11例高血压患者无需药物治疗血压得到良好控制,所有6例有血尿的患者血尿消失。
乙醇硬化治疗有症状的单纯性肾囊肿简单、微创且高效。我们推荐将其作为这些患者的首选治疗方法。