抗Ri抗体相关的眼阵挛-肌阵挛综合征与乳腺癌：一例病例报告及文献综述
Anti-Ri antibody opsoclonus-myoclonus syndrome and breast cancer: a case report and a review of the literature.
作者信息
Weizman David A, Leong Wey L
机构信息
General Surgery and Surgical Oncology, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada.
出版信息
J Surg Oncol. 2004 Sep 1;87(3):143-5. doi: 10.1002/jso.20103.
Opsoclonus-myoclonus is a rare neurological paraneoplastic syndrome associated with breast cancer and the presence of anti-Ri antibody. We presented a case of a 79-year-old woman with this syndrome and a small invasive ductal carcinoma [pT1aN0(sn)M0], whose symptoms improved 3 months following her simple mastectomy without any adjuvant therapy. Based on the 15 previously reported cases in the literature, there is no uniform treatment option available, and the response to such treatments is mixed.
眼阵挛-肌阵挛是一种罕见的神经系统副肿瘤综合征，与乳腺癌及抗Ri抗体的存在相关。我们报告了一例79岁患有该综合征及小灶浸润性导管癌[pT1aN0(sn)M0]的女性病例，其症状在单纯乳房切除术后3个月未接受任何辅助治疗的情况下有所改善。基于文献中先前报道的15例病例，目前尚无统一的治疗方案，且对此类治疗的反应不一。
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