Moriya Junji, Daimon Yumiko, Itoh Yuichi, Nakano Masayuki, Yamada Zenju
Division of Cardiology, Chiba National Hospital, Chiba.
J Cardiol. 2004 Jul;44(1):33-8.
A 60-year-old man was admitted to our hospital for evaluation of intracardiac vegetative masses detected by echocardiography in September 2001. He had undergone surgery for oral cavity cancer in 1999. He presented with severe embolic symptoms including cerebral infarction, but had few symptoms of heart failure. Antibiotic therapy was started under the diagnosis of infective endocarditis, but the embolic symptoms persisted. An autopsy revealed that the intracardiac vegetative masses consisted of tumor cells originating from the oral cavity cancer. Intravascular tumor thrombi were also found widely distributed in other organs such as the liver, lung, spleen and kidney, and had similar histological features. This is a very rare case of cardiac metastases of oral cavity cancer without adhesion to the endocardium or other myocardial tissue.
一名60岁男性于2001年9月因超声心动图检测到心内赘生物而入住我院。他曾于1999年接受口腔癌手术。他出现了包括脑梗死在内的严重栓塞症状,但几乎没有心力衰竭症状。在诊断为感染性心内膜炎后开始抗生素治疗,但栓塞症状持续存在。尸检显示心内赘生物由源自口腔癌的肿瘤细胞组成。血管内肿瘤血栓也广泛分布于肝脏、肺、脾和肾等其他器官,且具有相似的组织学特征。这是一例非常罕见的口腔癌心脏转移病例,肿瘤未附着于心内膜或其他心肌组织。