Wang Binbin, Zheng Baoshan, Zhai Cheng, Yu Guangqian, Liu Xiaojing
The State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China.
Environ Int. 2004 Oct;30(8):1067-73. doi: 10.1016/j.envint.2004.05.006.
In this project, the relationship between fluorine content in drinking water and dental health of residents in some large cities in China was evaluated. The concentration of fluorine in tap water and in urine of local subjects of 28 cities and 4 high fluorine villages in China shows a strong positive correlation (r(2)=0.96, S.E.=0.9881). Our studies indicate that drinking water is the most important source of fluorine intake for Chinese people, and in more than 90% of urban cities, fluorine concentrations in drinking water are below levels recommended by the WHO (approximately 0.5-1.0 mg/l). A 1995 investigation by The National Committee on Oral Health of China (NCOH) shows the relationship between average number of decayed, missing and filled teeth (DMFT) of urban residents and fluorine concentration in drinking water to be negatively correlated but not forming a good linear relationship. Our results, together with the previous study, suggest that: (1) dental caries of the study population can be reduced by drinking water fluoridation and that (2) other factors such as economic level, weather, lifestyle, food habits, living condition, etc., of a city can also affect the incidence of dental caries that cannot be predicted by fluoridation alone. Research on the relation between index of fluorosis (IF) and the fluorine concentration in drinking water for the four high fluorine villages showed that the recommended concentration of fluorine in drinking water can protect from dental fluorosis.
在本项目中,对中国一些大城市居民饮用水中的氟含量与牙齿健康之间的关系进行了评估。中国28个城市和4个高氟村当地居民的自来水和尿液中的氟浓度呈现出很强的正相关性(r(2)=0.96,标准误差=0.9881)。我们的研究表明,饮用水是中国人氟摄入的最重要来源,并且在90%以上的城市中,饮用水中的氟浓度低于世界卫生组织推荐的水平(约0.5 - 1.0毫克/升)。中国口腔健康全国委员会(NCOH)1995年的一项调查显示,城市居民的龋失补牙均数(DMFT)与饮用水中的氟浓度呈负相关,但未形成良好的线性关系。我们的研究结果与之前的研究共同表明:(1)通过饮用水加氟可降低研究人群的龋齿发生率;(2)一个城市的经济水平、天气、生活方式、饮食习惯、生活条件等其他因素也会影响龋齿的发生率,仅靠加氟无法预测。对4个高氟村的氟斑牙指数(IF)与饮用水中氟浓度之间关系的研究表明,推荐的饮用水氟浓度可预防氟斑牙。