Nordal Eli J, Christensen Ole B
Department of Dermatology, Ullevål University Hospital, Oslo, Norway.
Acta Derm Venereol. 2004;84(4):302-4. doi: 10.1080/00015550410025886.
UVB-TL01 is proven to be efficient in whole body treatment for several chronic inflammatory dermatoses. Chronic hand dermatoses of different and often mixed genesis represent a great problem in clinical practice. We have performed a prospective, open study with patients suffering from psoriasis, eczema or pustulosis of the hands treated with hand UVB-TL01. Thirty patients (23 women and 7 men) were included, mean age 43 years (range 25-68 years). The psoriatics were the best responders, as 9 of 11 were improved or much improved after 20-38 treatments, compared to 11 of 16 patients with eczema (11-31 treatments). One of three patients with palmar pustulosis experienced improvement after 23-27 treatments. UVB-TL01 seems to be helpful in the majority of patients with chronic inflammatory diseases of the hands. More extensive studies with regard to proper dosing and length of treatment period ought to be carried out.
UVB-TL01已被证明在全身治疗多种慢性炎症性皮肤病方面有效。不同病因且常混合存在的慢性手部皮肤病在临床实践中是一个重大问题。我们对患有手部银屑病、湿疹或脓疱病的患者进行了一项使用手部UVB-TL01的前瞻性开放性研究。纳入了30名患者(23名女性和7名男性),平均年龄43岁(范围25 - 68岁)。银屑病患者的反应最佳,11名患者中有9名在接受20 - 38次治疗后病情改善或显著改善,相比之下,16名湿疹患者中有11名(接受11 - 31次治疗)。3名掌跖脓疱病患者中有1名在接受23 - 27次治疗后病情改善。UVB-TL01似乎对大多数患有手部慢性炎症性疾病的患者有帮助。关于合适剂量和治疗周期长度应进行更广泛的研究。