钙波主导并划分放射状胶质细胞。

Calcium waves rule and divide radial glia.

作者信息

Yokota Yukako, Anton E S

机构信息

UNC Neuroscience Center, The University of North Carolina School of Medicine, Chapel Hill 27599, USA.

出版信息

Neuron. 2004 Sep 2;43(5):599-601. doi: 10.1016/j.neuron.2004.08.030.

DOI:10.1016/j.neuron.2004.08.030

PMID:15339639

Abstract

Radial glial proliferation is a critical step in the construction of cerebral cortex. In this issue of Neuron, Weissman and colleagues use time-lapse calcium imaging techniques to demonstrate that spontaneous calcium waves sweeping through cohorts of radial glia in the ventricular zone can modulate their proliferation during cerebral cortical development.

摘要

放射状胶质细胞增殖是大脑皮层构建中的关键步骤。在本期《神经元》杂志中，魏斯曼及其同事运用延时钙成像技术证明，在脑室区中，自发钙波席卷放射状胶质细胞群体时，可在大脑皮层发育过程中调节其增殖。