Bystron Irina, Blakemore Colin, Rakic Pasko
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, OX1 3PT, UK.
Nat Rev Neurosci. 2008 Feb;9(2):110-22. doi: 10.1038/nrn2252.
In 1970 the Boulder Committee described the basic principles of the development of the CNS, derived from observations on the human embryonic cerebrum. Since then, numerous studies have significantly advanced our knowledge of the timing, sequence and complexity of developmental events, and revealed important inter-species differences. We review current data on the development of the human cerebral cortex and update the classical model of how the structure that makes us human is formed.
1970年,博尔德委员会描述了中枢神经系统发育的基本原则,这些原则源自对人类胚胎大脑的观察。从那时起,大量研究显著推进了我们对发育事件的时间、顺序和复杂性的认识,并揭示了重要的种间差异。我们回顾了关于人类大脑皮层发育的当前数据,并更新了关于使我们成为人类的结构是如何形成的经典模型。