Ezrokhin V M, Shekhter A B, Nikitin A A, Bezdenezhnykh D S
Stomatologiia (Mosk). 2004;83(4):50-5.
Analysis of clinical characteristics of 56 patients with combined deformations of the nose and morphological (histological and histochemical) changes in the nasal septal cartilage in 20 patients showed that common nasal deformations are complicated with age, impeding nasal respiration. The intensity of dystrophic changes in chondrocytes and intercellular cartilaginous matrix depends on the duration of posttraumatic or congenital deformation but not on its clinical severity. This necessitates earlier interventions, before the development of pronounced deformation of the whole nose and deterioration of nasal respiration.
对56例鼻联合畸形患者的临床特征分析以及对20例鼻中隔软骨形态学（组织学和组织化学）变化的研究表明，常见的鼻畸形会随着年龄增长而复杂化，影响鼻呼吸。软骨细胞和细胞间软骨基质营养不良变化的强度取决于创伤后或先天性畸形的持续时间，而非其临床严重程度。这就需要在整个鼻子出现明显畸形和鼻呼吸恶化之前尽早进行干预。
