Engelmann L
Multidisziplinäres Zentrum für Intensivmedizin, Universitätsklinikum Leipzig.
Internist (Berl). 2004 Oct;45(10):1147-54. doi: 10.1007/s00108-004-1275-7.
The right ventricle is the stepchild of intensive care medicine. In diseases of the lung mainly when the relationship between ventilation and perfusion is disturbed, assisted respiration with positive end-expiratory pressure (PEEP) is essential to improve oxygenation. The serious damage to the lung parenchyma as seen in adult (acute) respiratory distress syndrome (ARDS) and pneumonia has considerable consequences for cardiac function. Whereas left ventricular function remains almost completely unaffected well into late stages of the disease, the right ventricle is subjected early to stress from the underlying disease and mechanical ventilation. The effects of therapeutic measures aimed at maintaining oxygenation and ventilation partially have negative consequences for right ventricular function and encourage the development of acute cor pulmonale. They can be the cause of right-sided heart failure.
右心室在重症监护医学中不受重视。在肺部疾病中，主要是当通气与灌注的关系受到干扰时，呼气末正压通气（PEEP）辅助呼吸对于改善氧合至关重要。在成人（急性）呼吸窘迫综合征（ARDS）和肺炎中所见的肺实质严重损伤对心脏功能有相当大的影响。虽然在疾病晚期左心室功能几乎完全不受影响，但右心室早期就受到基础疾病和机械通气的压力。旨在维持氧合和通气的治疗措施部分会对右心室功能产生负面影响，并促使急性肺心病的发展。它们可能是右侧心力衰竭的原因。
