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[急性呼吸窘迫综合征:基本原理与治疗]

[Acute respiratory distress syndrome : Basic principles and treatment].

作者信息

Spieth P M, Güldner A, Gama de Abreu M

机构信息

Klinik für Anästhesiologie und Intensivtherapie, Pulmonary Engineering Group, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

出版信息

Anaesthesist. 2017 Jul;66(7):539-552. doi: 10.1007/s00101-017-0337-x.

DOI:10.1007/s00101-017-0337-x
PMID:28677019
Abstract

Even after many years of intensive research acute respiratory distress syndrome (ARDS) is still associated with a high mortality. Epidemiologically, ARDS represents a central challenge for modern intensive care treatment. The multifactorial etiology of ARDS complicates the clear identification and evaluation of new therapeutic interventions. Lung protective mechanical ventilation and adjuvant therapies, such as the prone position and targeted extracorporeal lung support are of particular importance in the treatment of ARDS, depending on the severity of the disease. In order to guarantee an individualized and needs-adapted treatment, ARDS patients benefit from treatment in specialized centers.

摘要

即使经过多年的深入研究,急性呼吸窘迫综合征(ARDS)的死亡率仍然很高。从流行病学角度来看,ARDS是现代重症监护治疗面临的一项核心挑战。ARDS的多因素病因使得明确识别和评估新的治疗干预措施变得复杂。根据疾病的严重程度,肺保护性机械通气以及辅助治疗,如俯卧位和靶向体外肺支持,在ARDS的治疗中尤为重要。为了确保个体化和按需调整的治疗,ARDS患者在专科中心接受治疗会受益。

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The German ECMO inflation: when things other than health and care begin to rule medicine.德国的体外膜肺氧合(ECMO)扩张:当健康与医疗之外的因素开始主导医学时。
Intensive Care Med. 2016 Aug;42(8):1264-6. doi: 10.1007/s00134-016-4380-x. Epub 2016 Jun 6.
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Statins for the prevention and treatment of acute lung injury and acute respiratory distress syndrome: A systematic review and meta-analysis.他汀类药物用于预防和治疗急性肺损伤及急性呼吸窘迫综合征:一项系统评价和荟萃分析。
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Personalized medicine for ARDS: the 2035 research agenda.
Correlation Analysis between Mechanical Power and Lung Ultrasound Score and Their Evaluation of Severity and Prognosis in ARDS Patients.
机械功率与肺部超声评分的相关性分析及其对 ARDS 患者严重程度和预后的评估。
Biomed Res Int. 2021 Sep 1;2021:4156162. doi: 10.1155/2021/4156162. eCollection 2021.
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[Effects of positive end-expiratory pressure setting of mechanical ventilation guided by esophageal pressure in the treatment of patients with traumatic craniocerebral injury combined with acute respiratory distress syndrome].[食管压力引导下机械通气呼气末正压设置对创伤性颅脑损伤合并急性呼吸窘迫综合征患者的治疗效果]
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Effect of Deep Sedation on Mechanical Power in Moderate to Severe Acute Respiratory Distress Syndrome: A Prospective Self-Control Study.深度镇静对中重度急性呼吸窘迫综合征机械功率的影响:一项前瞻性自身对照研究。
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Ventilator for the treatment of acute respiratory distress syndrome: A protocol for systematic review and meta-analysis.用于治疗急性呼吸窘迫综合征的呼吸机:系统评价与荟萃分析方案
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[Certain and controversial components of "rapid sequence induction"].["快速序贯诱导麻醉中的确定与争议成分"]
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急性呼吸窘迫综合征的个性化医疗:2035年研究议程。
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The standard of care of patients with ARDS: ventilatory settings and rescue therapies for refractory hypoxemia.急性呼吸窘迫综合征患者的护理标准:通气设置及难治性低氧血症的抢救治疗
Intensive Care Med. 2016 May;42(5):699-711. doi: 10.1007/s00134-016-4325-4. Epub 2016 Apr 4.
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Extracorporeal membrane oxygenation: evolving epidemiology and mortality.体外膜肺氧合:不断变化的流行病学和死亡率。
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