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[急性呼吸窘迫综合征:基本原理与治疗]

[Acute respiratory distress syndrome : Basic principles and treatment].

作者信息

Spieth P M, Güldner A, Gama de Abreu M

机构信息

Klinik für Anästhesiologie und Intensivtherapie, Pulmonary Engineering Group, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

出版信息

Anaesthesist. 2017 Jul;66(7):539-552. doi: 10.1007/s00101-017-0337-x.

Abstract

Even after many years of intensive research acute respiratory distress syndrome (ARDS) is still associated with a high mortality. Epidemiologically, ARDS represents a central challenge for modern intensive care treatment. The multifactorial etiology of ARDS complicates the clear identification and evaluation of new therapeutic interventions. Lung protective mechanical ventilation and adjuvant therapies, such as the prone position and targeted extracorporeal lung support are of particular importance in the treatment of ARDS, depending on the severity of the disease. In order to guarantee an individualized and needs-adapted treatment, ARDS patients benefit from treatment in specialized centers.

摘要

即使经过多年的深入研究,急性呼吸窘迫综合征(ARDS)的死亡率仍然很高。从流行病学角度来看,ARDS是现代重症监护治疗面临的一项核心挑战。ARDS的多因素病因使得明确识别和评估新的治疗干预措施变得复杂。根据疾病的严重程度,肺保护性机械通气以及辅助治疗,如俯卧位和靶向体外肺支持,在ARDS的治疗中尤为重要。为了确保个体化和按需调整的治疗,ARDS患者在专科中心接受治疗会受益。

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