Terashima Jun, Bownes Mary
Institute of Cell and Molecular Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom.
Genetics. 2004 Aug;167(4):1711-9. doi: 10.1534/genetics.103.024323.
In Drosophila and other insects egg production is related to the nutrients available. Somehow the nutritional status of the environment is translated into hormonal signs that can be "read" by each individual egg chamber, influencing the decision to either develop into an egg or die. We have shown that BR-C is a control gene during oogenesis and that the differential expression of BR-C isoforms plays a key role in controlling whether the fate of the egg chamber is to develop or undergo apoptosis.
在果蝇和其他昆虫中,卵子的产生与可获得的营养物质有关。环境的营养状况以某种方式转化为激素信号,每个卵室都能“读取”这些信号,从而影响其发育成卵子或死亡的决定。我们已经表明,BR-C是卵子发生过程中的一个控制基因,BR-C同工型的差异表达在控制卵室的命运是发育还是经历凋亡方面起着关键作用。