Yi Ping, Sun Qing Ping, Wan Cui Xiang, Zhu Ying Guo
The Key Laboratory of MOE for Plant Developmental Biology and Institute of Genetics, College of Life Sciences, Wuhan University, Wuhan 430072.
Shi Yan Sheng Wu Xue Bao. 2002 Jun;35(2):123-6.
The term RNA editing is generally used to describe those molecular processes in which the information content is altered in an RNA molecule. This process is not limited to mRNA since alterations of non-informational RNA have also been found. RNA editing exists extensively in the higher plant mitochondria, and is the necessary step for forming functional proteins. In this paper, the research materials are the gametopthyte male sterility line (A), maintainer line (B) and F1 hybrid (F1) of HL-type CMS. 15 editing sites are found in the transcripts of coxII by comparing cDNAs and DNAs sequences. A,B and F1 have same Editing sites. When editing occurs at the first or second position of codons, the encoded amino acid is likely to be altered. As a result, the conservation of the predicted protein is improved as compared with other organisms.
术语“RNA编辑”通常用于描述那些RNA分子中信息内容发生改变的分子过程。该过程并不局限于mRNA，因为非信息性RNA的改变也已被发现。RNA编辑广泛存在于高等植物线粒体中，是形成功能蛋白的必要步骤。本文的研究材料是HL型细胞质雄性不育系（A）、保持系（B）和F1杂种（F1）。通过比较cDNA和DNA序列，在coxII转录本中发现了15个编辑位点。A、B和F1具有相同的编辑位点。当编辑发生在密码子的第一位或第二位时，编码的氨基酸可能会发生改变。结果，与其他生物相比，预测蛋白质的保守性得到了提高。
