Petkovska L, Ramadan S, Aslam M O
Radiology Department, Al-Adan Hospital, Safat 5326, Kuwait.
Australas Radiol. 2004 Sep;48(3):408-10. doi: 10.1111/j.0004-8461.2004.01329.x.
Cherubism is a rare autosomal dominant fibro-osseous disorder of childhood, mostly limited to the maxilla and mandible. Extra-cranial skeletal involvement is rare. Post-pubertal involution of the process and jaw remodeling occurs in adulthood. The aim of this case report is to present four cherubs, a father and his three daughters, in whom the diagnosis was made based on history, physical examination, laboratory tests and typical radiological features. The imaging characteristics are discussed and the published literature is reviewed.
cherubism是一种罕见的儿童常染色体显性遗传性纤维-骨疾病，主要局限于上颌骨和下颌骨。颅外骨骼受累罕见。青春期后病情会逐渐消退，成年后颌骨会重塑。本病例报告旨在介绍4例cherubism患者，即一位父亲及其3个女儿，他们的诊断是基于病史、体格检查、实验室检查和典型的放射学特征做出的。文中讨论了其影像学特征并回顾了已发表的文献。
