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cherubism:来自一个家族的20例病例研究

Cherubism: a study of twenty cases from one family.

作者信息

Peters W J

出版信息

Oral Surg Oral Med Oral Pathol. 1979 Apr;47(4):307-11. doi: 10.1016/0030-4220(79)90251-2.

DOI:10.1016/0030-4220(79)90251-2
PMID:285398
Abstract

A study involving twenty cherubs, members of one family, is presented. The autosomal dominance pattern of inheritance is confirmed, while the penetrance is shown to be 80 percent. Clinical presentation and characteristics are discussed, together with histologic findings which reveal the giant-cell nature of the lesions. Conservative management is advocated, with emphasis placed on avoidance of radiotherapy.

摘要

本文介绍了一项对来自同一个家族的20名儿童进行的研究。确认了常染色体显性遗传模式,同时显示其外显率为80%。文中讨论了临床表现和特征,以及揭示病变巨细胞性质的组织学发现。提倡采取保守治疗,重点是避免放疗。

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