Durovicová J, Puzová H, Janigová V, Nistiar F, Kmetová M
Katedra mikrobiológie Lekárskej fakulty, Univerzity P.J. Safárika v Kosiciach.
Cesk Epidemiol Mikrobiol Imunol. 1992 Apr;41(1):30-4.
The authors focused attention on testing of biological properties of alpha-haemolytic strains of E. coli in infections of the urinary pathways in children and on the antibody response against alpha-haemolysin. The strains belonged into serogroups 02, 04, 06, 018, 075, 0112. The majority of strains had fimrial adhesins, i.e. P fimbriae, or fimbriae type 1. Alpha-haemolysin one of the factors of UPEC virulence induces anti-alphahaemolysin formation in serum (ANTI AH). Titres of ANTI AH in sera of children with acute uroinfection were from 1:32 to 1:1024. Lower titres were recorded in infections of the lower urinary pathways higher ones in renal infections, whereby the dynamics of ANTI AH titres depend on the development of the disease.
作者将注意力集中在对儿童泌尿道感染中大肠杆菌α-溶血菌株生物学特性的检测以及针对α-溶血素的抗体反应上。这些菌株属于血清群02、04、06、018、075、0112。大多数菌株具有菌毛黏附素，即P菌毛或1型菌毛。α-溶血素是尿道致病性大肠杆菌（UPEC）毒力因子之一，可诱导血清中抗α-溶血素的形成（ANTI AH）。急性尿路感染患儿血清中ANTI AH的滴度为1:32至1:1024。下泌尿道感染时记录到的滴度较低，肾脏感染时滴度较高，ANTI AH滴度的动态变化取决于疾病的发展。
