Zaun H, Omlor G
Hautklinik, Universität des Saarlandes, Homburg/Saar.
Hautarzt. 1992 Apr;43(4):215-6.
We report on a patient with simultaneous manifestation of two different side-effects of a cytostatic therapy, which have to be ascribed to cytotoxic influences of different intensity. In this 37-year-old woman, "Mees-like" transverse white bands appeared on all the nails on the left hand after isolated cytostatic perfusion of the left arm. The nails on the right hand and the feet remained free of visible changes. However, the low doses of cytostatic drugs shunted into the systematic circulation induced diffuse toxic hair loss.
我们报告了一名患者,其同时出现了细胞抑制疗法的两种不同副作用,这两种副作用必须归因于不同强度的细胞毒性影响。在这名37岁的女性患者中,左臂单独进行细胞抑制灌注后,左手所有指甲上出现了“米氏线样”横向白色条纹。右手和双脚的指甲未见明显变化。然而,进入体循环的低剂量细胞抑制药物导致了弥漫性中毒性脱发。