Schuitemaker G E, Dinant G J, van der Pol G A, Appels A
Department of General Practice, University of Maastricht, The Netherlands.
Psychosomatics. 2004 Sep-Oct;45(5):414-8. doi: 10.1176/appi.psy.45.5.414.
Vital exhaustion, a state characterized by unusual fatigue, loss of energy, increased irritability, and feelings of demoralization, is one of the cardiovascular risk factors. The authors investigated whether vital exhaustion contributes to the identification of subjects at increased risk of myocardial infarction in general practice. In this prospective cohort study, vital exhaustion was assessed with the Maastricht Interview on Vital Exhaustion. Other cardiovascular risk factors established were age, gender, systolic and diastolic blood pressure, total cholesterol, body mass index, smoking habits, cardiovascular disease, and diabetes mellitus. A Cox regression analysis was used. The subjects were adults (41-66 years) in an average Dutch village population. Outcome measures were fatal and nonfatal myocardial infarction. At the univariate level, vital exhaustion doubled the risk of myocardial infarction. The effect of exhaustion was confounded by gender; women had higher exhaustion scores and a lower incidence of myocardial infarction. With control for gender, age, systolic blood pressure, total cholesterol, smoking habits, self-reported cardiovascular disease, and diabetes mellitus, vital exhaustion almost tripled the risk of myocardial infarction. Assessment of vital exhaustion contributes to the identification of subjects at increased risk of myocardial infarction in general practice.
精力耗竭是一种以异常疲劳、精力丧失、易怒加剧和士气低落为特征的状态，是心血管危险因素之一。作者调查了在一般医疗实践中，精力耗竭是否有助于识别心肌梗死风险增加的受试者。在这项前瞻性队列研究中，使用马斯特里赫特精力耗竭访谈来评估精力耗竭情况。已确定的其他心血管危险因素包括年龄、性别、收缩压和舒张压、总胆固醇、体重指数、吸烟习惯、心血管疾病和糖尿病。采用Cox回归分析。研究对象是荷兰一个普通乡村的成年人（41 - 66岁）。观察指标为致命性和非致命性心肌梗死。在单变量水平上，精力耗竭使心肌梗死风险加倍。精力耗竭的影响因性别而混淆；女性精力耗竭得分更高，心肌梗死发病率更低。在控制了性别、年龄、收缩压、总胆固醇、吸烟习惯、自我报告的心血管疾病和糖尿病后，精力耗竭使心肌梗死风险几乎增加两倍。在一般医疗实践中，评估精力耗竭有助于识别心肌梗死风险增加的受试者。
