T 系急性淋巴细胞白血病之前的短暂全血细胞减少症。
Transient pancytopenia preceding T lineage acute lymphoblastic leukemia.
作者信息
Zhao Hui, Zhang Li, Zhu Xiaofan, Chen Yumei, Zou Yao, Zhang Lei, Yang Renchi, Han Zhong Chao
机构信息
Department of Thrombosis and Hemostasis, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, PR China.
出版信息
Acta Haematol. 2004;112(3):167-9. doi: 10.1159/000079730.
Transient pancytopenia preceding acute lymphoblastic leukemia (pre-ALL) is a rare occurrence usually affecting children with subsequent development of B lineage ALL. We report a case of pre-ALL characterized by a T cell immunophenotype and abnormal karyotype t (11; 14) (q10; q10). The patient achieved a transient complete remission after initial therapy, but relapsed within a few months and died of leukemic encephalopathy. To the best of our knowledge, this is the first report of T lineage pre-ALL.
急性淋巴细胞白血病（ALL）前期的短暂全血细胞减少症是一种罕见的情况，通常影响儿童，随后会发展为B系ALL。我们报告了一例ALL前期病例，其特征为T细胞免疫表型和异常核型t（11；14）（q10；q10）。该患者在初始治疗后实现了短暂的完全缓解，但在几个月内复发，并死于白血病性脑病。据我们所知，这是T系ALL前期的首例报告。
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