Timonen J, Kippo K, Glantz R, Pakkanen T
University of Joensuu, Department of Chemistry, P.O. Box 111, FIN-80140 Joensuu, Finland.
J Mater Sci Mater Med. 2001 Apr;12(4):319-25. doi: 10.1023/a:1011295020550.
Three dimensional (3-D) magnetic resonance (MR) microimaging combined with connectivity analysis was tested in the study of the structure of cancellous bone. MR microimaging was performed in vitro with an average resolution of 202035 microm. A 3-D connectivity analysis was used to model the trabecular bone as a network consisting of nodes and struts. Size distribution curves of these two structural elements and the interconnectivity of nodes was used to estimate the cancellous structure. The analysis suggested the occurrence of two simultaneous network structures in cancellous bone differed by the size of details. The degradative effect of ostcopenia is found to be slightly different in these two subsystems. Interconnectivity is seen to increase with the size of a node and the expected loss of connectivity due to ostcopenia is observed. The method described offers a new way in the topological estimation of interconnected medium.
在松质骨结构研究中对三维（3-D）磁共振（MR）显微成像结合连通性分析进行了测试。MR显微成像在体外进行，平均分辨率为20×20×35微米。使用三维连通性分析将小梁骨建模为由节点和支柱组成的网络。这两个结构元素的尺寸分布曲线以及节点的互连性用于估计松质结构。分析表明，松质骨中同时存在两种网络结构，其细节尺寸不同。在这两个子系统中发现骨质减少的降解作用略有不同。可以看到互连性随节点大小增加，并且观察到由于骨质减少导致的预期连通性损失。所描述的方法为互连介质的拓扑估计提供了一种新途径。
