Monheit Blythe E, Fiveash John B, Girkin Christopher A
Department of Ophthalmology, University of Alabama-Birmingham, 700 18th Street S. , Birmingham, AL 35233, USA.
J Neuroophthalmol. 2004 Sep;24(3):195-9. doi: 10.1097/00041327-200409000-00002.
A patient had bilateral superior altitudinal visual field defects because of radionecrosis of the inferior occipital lobes after gamma knife radiosurgery for a recurrent atypical cerebellar meningioma. Although radionecrosis of the anterior visual pathway has been well-documented, this is the first report of visual field loss associated with occipital lobe radionecrosis. The treatment dose this patient received is within the range of predicted tolerable radiosurgical dosing, although this patient was at increased risk for radionecrosis secondary to previous external beam radiotherapy. By offering an effective, noninvasive treatment, radiosurgery has changed the management of intracranial lesions. Radiosurgery targets a discrete volume of tissue and relatively spares the surrounding normal tissue. Radiation injury, or radionecrosis, is the only significant complication of radiosurgery (). We present a case of bilateral occipital lobe radionecrosis after gamma knife surgery that resulted in bilateral superior altitudinal defects.
一名患者在接受伽玛刀放射治疗复发性非典型小脑脑膜瘤后,因枕叶下部放射性坏死出现双侧上象限视野缺损。尽管视觉通路前部的放射性坏死已有充分记录,但这是与枕叶放射性坏死相关的视野缺损的首例报告。该患者接受的治疗剂量在预测的可耐受放射外科剂量范围内,尽管该患者因先前接受过外照射放疗而发生放射性坏死的风险增加。放射外科通过提供一种有效、无创的治疗方法,改变了颅内病变的治疗方式。放射外科针对离散的组织体积,相对 sparing 周围正常组织。辐射损伤或放射性坏死是放射外科唯一的重要并发症()。我们报告一例伽玛刀手术后双侧枕叶放射性坏死导致双侧上象限缺损的病例。