Pérez-Espejo M A, García-Fernández R, Tobarra-González B M, Palma-Copete J D, González-López A, De la Fuente-Muñoz I, Salinas-Ramos J, Felipe-Murcia M, Martínez-Lage J F, Fernández-Pérez J, Romero J M
Servicios de Neurocirugía. Hospital Universitario "Virgen Arrixaca". Murcia. España.
Neurocirugia (Astur). 2009 Oct;20(5):449-53.
Radionecrosis with brain edema is a complication of radiosurgery. Three female patients harbouring a frontal pole, petrous and parasagital parietoocipital meningiomas respectively who had been treated with LINAC radiosurgery are presented. Those patients developed, between two and eight months later, a severe symptomatic radionecrosis with a huge brain edema resistant to the usual steroid therapy. Only after 40 sessions of hyperbaric oxygen, a good remission of the lesions was obtained. There are few cases reported in the literature with such a good outcome. Consequentely, this therapy must be taken into account to treat this type of radiosurgical complication before considering surgery.
放射性坏死伴脑水肿是放射外科手术的一种并发症。本文介绍了三名分别患有额极、岩部和矢状窦旁顶枕部脑膜瘤的女性患者，她们均接受了直线加速器放射外科治疗。这些患者在治疗后两到八个月内出现了严重的症状性放射性坏死，并伴有巨大的脑水肿，常规类固醇治疗无效。仅在接受40次高压氧治疗后，病变才得到良好缓解。文献中报道的此类良好结果的病例很少。因此，在考虑手术之前，必须考虑采用这种疗法来治疗这类放射外科并发症。
