Roddy E, Zhang W, Doherty M, Arden N K, Barlow J, Birrell F, Carr A, Chakravarty K, Dickson J, Hay E, Hosie G, Hurley M, Jordan K M, McCarthy C, McMurdo M, Mockett S, O'Reilly S, Peat G, Pendleton A, Richards S
Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK.
Rheumatology (Oxford). 2005 Jan;44(1):67-73. doi: 10.1093/rheumatology/keh399. Epub 2004 Sep 7.
OBJECTIVES: Exercise is an effective and commonly prescribed intervention for lower limb osteoarthritis (OA). Many unanswered questions remain, however, concerning the practical delivery of exercise therapy. We have produced evidence-based recommendations to guide health-care practitioners. METHODS: A multidisciplinary guideline development group was formed from representatives of professional bodies to which OA is of relevance and other interested parties. Each participant contributed up to 10 propositions describing key clinical points regarding exercise therapy for OA of the hip or knee. Ten final recommendations were agreed by the Delphi technique. The research evidence for each was determined. A literature search was undertaken in the Medline, PubMed, EMBASE, PEDro, CINAHL and Cochrane databases. The methodological quality of each retrieved publication was assessed. Outcome data were abstracted and effect sizes calculated. The evidence for each recommendation was assessed and expert consensus highlighted by the allocation of two categories: (1) strength of evidence and (2) strength of recommendation. RESULTS: The first round of the Delphi process produced 123 propositions. This was reduced to 10 after four rounds. These related to aerobic and strengthening exercise, group versus home exercise, adherence, contraindications and predictors of response. The literature search identified 910 articles; 57 intervention trials relating to knee OA, 9 to hip OA and 73 to adherence. The evidence to support each proposition is presented. CONCLUSION: These are the first recommendations for exercise in hip and knee OA to clearly differentiate research evidence and expert opinion. Gaps in the literature are identified and issues requiring further study highlighted.
目的:运动是治疗下肢骨关节炎(OA)的一种有效且常用的干预措施。然而,关于运动疗法的实际实施仍存在许多未解决的问题。我们制定了基于证据的建议,以指导医疗保健从业者。 方法:一个多学科指南制定小组由与OA相关的专业机构代表和其他相关方组成。每位参与者提出了多达10条关于髋部或膝部OA运动疗法关键临床要点的提议。通过德尔菲技术达成了10条最终建议。确定了每条建议的研究证据。在Medline、PubMed、EMBASE、PEDro、CINAHL和Cochrane数据库中进行了文献检索。评估了每篇检索到的出版物的方法学质量。提取了结果数据并计算了效应量。通过分配两类来评估每条建议的证据并突出专家共识:(1)证据强度和(2)建议强度。 结果:德尔菲过程的第一轮产生了123条提议。经过四轮后减少到10条。这些提议涉及有氧运动和强化运动、团体运动与家庭运动、依从性、禁忌症和反应预测因素。文献检索确定了910篇文章;57项与膝OA相关的干预试验,9项与髋OA相关的试验,73项与依从性相关的试验。列出了支持每条提议的证据。 结论:这些是关于髋部和膝部OA运动的首批建议,明确区分了研究证据和专家意见。确定了文献中的空白,并突出了需要进一步研究的问题。
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