[α1受体阻滞剂治疗良性前列腺增生症的研究进展]

[Progress in the studies of alpha1-receptor blocker for benign prostatic hyperplasia].

作者信息

Sun Yinghao

机构信息

Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

出版信息

Zhonghua Nan Ke Xue. 2004 Jul;10(7):483-5.

Abstract

Benign prostatic hyperplasia (BPH) is a common senile disease, and its main clinical manifestation is lower urinary tract symptom (LUTS), which has long been afflicting old male patients. Previous study showed that alpha1-receptor in the prostate was involved in the development of LUTS. At present, alpha1-receptor blocker is generally accepted as a choice drug for treating BPH and relieving LUTS. The article reviews the tissue distribution of alpha1-receptor and clinical application of alpha1-receptor blocker.

摘要

良性前列腺增生（BPH）是一种常见的老年疾病，其主要临床表现为下尿路症状（LUTS），长期困扰着老年男性患者。先前的研究表明，前列腺中的α1受体参与了LUTS的发生发展。目前，α1受体阻滞剂被普遍认为是治疗BPH和缓解LUTS的首选药物。本文综述了α1受体的组织分布及α1受体阻滞剂的临床应用。

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