3岁、7岁、10岁和12岁时问题行为稳定性和变化背后的遗传和环境机制。
Genetic and environmental mechanisms underlying stability and change in problem behaviors at ages 3, 7, 10, and 12.
作者信息
Bartels M, van den Oord E J C G, Hudziak J J, Rietveld M J H, van Beijsterveldt C E M, Boomsma D I
机构信息
Department of Biological Psychology, Vrije Universiteit, Amsterdam, Netherlands.
出版信息
Dev Psychol. 2004 Sep;40(5):852-67. doi: 10.1037/0012-1649.40.5.852.
Maternal ratings on internalizing (INT) and externalizing (EXT) behaviors were collected in a large, population-based longitudinal sample. The numbers of participating twin pairs at ages 3, 7, 10, and 12 were 5,602, 5,115, 2,956, and 1,481, respectively. Stability in both behaviors was accounted for by genetic and shared environmental influences. The genetic contribution to stability (INT: 43%; EXT: 60%) resulted from the fact that a subset of genes expressed at an earlier age was still active at the next time point. A common set of shared environmental factors operated at all ages (INT: 47%; EXT: 34%). The modest contribution of nonshared environmental factors (INT: 10%; EXT: 6%) could not be captured by a simple model. Significant age-specific influences were found for all components, indicating that genetic and environmental factors also contributed to changes in problem behavior.
在一个基于人群的大型纵向样本中收集了母亲对内化（INT）和外化（EXT）行为的评分。3岁、7岁、10岁和12岁时参与的双胞胎对数量分别为5602对、5115对、2956对和1481对。两种行为的稳定性由遗传和共享环境影响来解释。对稳定性的遗传贡献（INT：43%；EXT：60%）源于这样一个事实，即较早年龄表达的一部分基因在接下来的时间点仍然活跃。一组共同的共享环境因素在所有年龄段都起作用（INT：47%；EXT：34%）。非共享环境因素的适度贡献（INT：10%；EXT：6%）无法用一个简单模型来捕捉。所有成分都发现了显著的年龄特异性影响，表明遗传和环境因素也导致了问题行为的变化。
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