法国出现属于序列型1403的B群脑膜炎奈瑟菌：15：P1.12疫情。

Outbreak in France of Neisseria meningitidis B:15:P1.12 belonging to sequence type 1403.

作者信息

Grodet C, Dequin P F, Watt S, Lanotte P, de Gialluly C, Taha M K, Alonso J M, Quentin R, Goudeau A, Mereghetti L

机构信息

Service de Bactériologie et Hygiène Hospitalière, Hôpital Trousseau, Tours, France.

出版信息

Clin Microbiol Infect. 2004 Sep;10(9):845-8. doi: 10.1111/j.1469-0691.2004.00935.x.

DOI:10.1111/j.1469-0691.2004.00935.x

PMID:15355418

Abstract

This report describes a meningococcal outbreak in France caused by Neisseria meningitidis B:15:P1.12 of sequence type 1403, which affected eight young patients, between November 2000 and February 2002. Epidemiological typing confirmed that a single strain was responsible. Favourable outcome, sequelae or death resulted in similar proportions as in other cases of meningococcal disease in France during the same period, but purpura was observed in all eight cases. The patients were aged between 14 and 28 years, whereas the median age of patients affected by other meningococcal strains during this period in the same area was 60.4 years.

摘要

本报告描述了2000年11月至2002年2月期间在法国发生的由序列型1403的B:15:P1.12型脑膜炎奈瑟菌引起的脑膜炎球菌暴发，该疫情影响了8名年轻患者。流行病学分型证实系单一菌株所致。与同期法国其他脑膜炎球菌病病例相比，好转、后遗症或死亡的比例相似，但8例患者均出现紫癜。患者年龄在14至28岁之间，而同一时期该地区受其他脑膜炎球菌菌株感染患者的年龄中位数为60.4岁。