McClelland H R, Quinn A J
Gynaecological Unit, Ulster Hospital, Dundonald, Belfast.
Ulster Med J. 1992 Apr;61(1):51-5.
Six patients with large uterine fibroids were given a single subcutaneous implant of an LHRH analogue (goserelin 3.5 mg) prior to elective hysterectomy. Overall fibroid volume decreased by 30-47% within six weeks of implantation. All patients reported improvement in their symptoms of pressure and pain, and were rendered amenorrhoeic prior to surgery.
6例患有大型子宫肌瘤的患者在择期子宫切除术前接受了一次皮下植入促性腺激素释放激素(LHRH)类似物(戈舍瑞林3.5毫克)。植入后六周内肌瘤总体积减少了30%至47%。所有患者均报告其压迫和疼痛症状有所改善,并且在手术前闭经。